ABSTRACT
In the process of pharmacokinetic/pharmacodynamic (PK/PD) modeling, it is important to describe, prospectively, the objectives of the modeling, the study design, and the available PK and PD data. The assumptions of the model can be related to dose-response, PK, PD, or one or more of the assumptions listed in Table 4.1. A PK/PD model can be related to dose-response, to PK, to PD, or to one or more of the following assumptions.
