ABSTRACT

Evolutionary biology has increasingly relied upon tools developed in molecular biology that allow for the structure and function of macromolecules to be used as data for exploring the patterns and processes of evolutionary change. Integrated Molecular Evolution, Second Edition is a textbook intended to expansively and comprehensive review evolutionary studies now routinely using molecular data. This new edition has been thoroughly updated and expanded, and provides a basic summary of evolutionary biology as well as a review of current phylogenetics and phylogenomics.

Reflecting a burgeoning pedagogical landscape, this new edition includes nearly double the number of chapters, including a new section on molecular and bioinformatic methods. Dedicated chapters were added on:

  • Evolution of the genetic code
  • Mendelian genetics and population genetics
  • Natural selection
  • Horizontal gene transfers
  • Animal development and plant development
  • Cancer
  • Extraction of biological molecules
  • Analytical methods
  • Sequencing methods and sequencing analyses
  • Omics
  • Phylogenetics and phylogenetic networks
  • Protein trafficking
  • Human genomics

More than 400 illustrations appear in this edition, doubling the number included in the first edition, and over 100 of these diagrams are now in color.

The second edition combines and integrates extensive summaries of genetics and evolutionary biology in a manner that is accessible for students at either the graduate or undergraduate level. It also provides both the basic foundations of molecular evolution, such as the structure and function of DNA, RNA and proteins, as well as more advanced chapters reviewing analytical techniques for obtaining sequences, and interpreting and archiving molecular and genomic data.

part |2 pages

SECTION I Life and Evolution

chapter 1|16 pages

Definitions of Life

chapter 2|20 pages

Earth and Evolution

part |2 pages

SECTION II Biomolecules

chapter 3|16 pages

DNA, RNA, and Proteins

chapter 4|14 pages

The Central Dogma and Beyond

chapter 5|12 pages

Ribosomes and Ribosomal RNA

chapter 6|14 pages

Structure of the Genetic Code

chapter 7|14 pages

DNA Replication

chapter 8|18 pages

DNA Segregation

part |2 pages

SECTION III Genetics

chapter 9|16 pages

Mendelian and Non-Mendelian Characters

chapter 10|12 pages

Population Genetics

chapter 11|14 pages

Alleles through Time

chapter 12|14 pages

Changes to DNA

part |2 pages

SECTION IV Multicellularity

chapter 14|14 pages

Multigene Families

chapter 15|18 pages

Horizontal Gene Transfer

chapter 17|22 pages

Development: Part II—Plants

chapter 18|20 pages

Cancer

part |2 pages

SECTION V Molecular Biology and Bioinformatic Methods

chapter 21|16 pages

Sequencing and Alignment Methods

chapter 22|10 pages

Omics: Part I

chapter 23|10 pages

Omics: Part II

chapter 24|26 pages

Species Concepts and Phylogenetics

chapter 26|14 pages

Phylogenomics and Comparative Genomics

part |2 pages

SECTION VI Genomes

chapter 27|16 pages

RNA Viruses

chapter 28|14 pages

DNA Viruses

chapter 29|10 pages

Bacteria and Archaea

chapter 30|10 pages

Mutualists and Pathogens

chapter 31|20 pages

Endosymbionts and Organelles

chapter 32|12 pages

Protein Trafficking

chapter 33|18 pages

Eukaryotic Genomes

chapter 34|12 pages

Human Genome