ABSTRACT
It has been found the antimicrobic activity of liposomal lincomycin depends on the composition and charge of liposomes. The antimicrobic activity of liposomal lincomycin, obtained on the basis of egg lecithin is higher than antimicrobic activity of the solution lincomycin in three times concerning planktonic cells of Staphylococcus aureus. Negatively charged liposomes received on the basis of polar lipids and lincomycins were more effective, than neutral liposomes. The minimum inhibitory concentration (MIC) of them is less of MIC of lincomycin in seven times concerning planktonic cells of Staphylococcus aureus. The antimicrobic activity of liposomal benzoyl peroxide (BP) obtained on the basis of egg lecithin was in 14 times higher than antimicrobic activity of the solution BP concerning of Staphylococcus aureus.
