ABSTRACT

Biomaterials are generally natural substances apart from food or drugs present in therapeutic or diagnostic systems that are in contact with tissue or biological uids.1 Polysaccharide-derived polymers display perfect biocompatibility and biodegradability, which are the basic requisites for polymers used as biomaterials. In carbohydrate-based polymeric systems, the drug is embedded in a polymer matrix and surgically implanted. The matrix may be biodegradable or nonbiodegradable. Hydrophilic polysaccharide carriers remain a highly popular design of modied release dosage form. Drug delivery systems containing polysaccharide excipient system was found to be capable of assuming different formulations and use in process methods to provide a variety of different release modalities independent of matrix-dimension.