ABSTRACT
PATHOPHYSIOLOGY OF RHEUMATOID ARTHRITIS 1. Which one of the following tissues is primarily affected in rheumatoid arthritis?
A. Articular cartilage B. Periosteum C. Bone
D. Tendon E. Synovium
DIAGNOSING RHEUMATOID ARTHRITIS 2. You see a 50-year-old woman in clinic with a 4-week history of bilateral wrist
and elbow joint stiffness that is worse in the morning. She is a nonsmoker and is otherwise fit and well. Recent blood tests show her to be seronegative for rheumatoid factor. Which one of the following is correct? A. She meets the criteria for a diagnosis of rheumatoid arthritis. B. Her blood test result excludes a diagnosis of rheumatoid arthritis. C. Her risk of developing rheumatoid arthritis is double that of an equivalent male. D. Her smoking history is not relevant to a diagnosis of rheumatoid disease E. Joint space narrowing on plain radiographs will confirm her diagnosis.
