ABSTRACT
Cutaneous melanoma metastases (CMMM) are considered a frequent event among melanoma patients; they can appear in about 20% of patients, and at any stage of disease. Amelanotic CMMMs can be even more difficult to differentiate from other skin lesions, such as nonspecific erythematous papules or nodules. The most significant dermoscopic features associated with a CMMM are the blue homogeneous and reddish saccular and vascular patterns, together with a pigmented halo and peripheral grey spots. The angioma-like pattern usually presents some degree of reddish or blue-purple pigmentation and ill-defined lacunar structures, with or without atypical vessels inside. One clue to differentiate angioma-like CMMMs from true angiomas is the absence of lacunae clearly separated by fibrous tracts. Amelanotic CMMM usually presents atypical vascular features, the most frequent being serpentine or linear irregular vessels, glomerular vessels, irregular hairpin, and corkscrew-like vessels. CMMM should be considered when any new persistent and/or rapidly growing erythematous lesion appears in patients with a previous invasive melanoma.
