ABSTRACT

HISTORY AND INDICATIONS FOR OOCYTE DONATION In vitro fertilization (IVF) has been an established treatment option for couples challenged by infertility since 1978.1 However, some couples may not be able to conceive using their own eggs. Most frequently, the reason is the advanced maternal age when no eggs or no viable eggs can be obtained. Less frequently, menopause can start early due to premature ovarian failure. Additionally, ovaries can be dysfunctional due to certain medical conditions, or as a result of treatment against cancer. In all of these situations, using donor egg is indicated. In some genetically inheritable conditions (present in the wife/female partner), the couple may also opt for donor oocytes, instead of using their own.2