ABSTRACT

Pencil beam-based dose calculation has been widely adopted in modern treatment planning system, because of its simple calculation scheme and acceptable accuracy in most clinical application. is simple and accurate dose calculation model will have extensive applications in online adaptive radiotherapy (ART), where the attractive concept of

CONTENTS 14.1 Introduction 225 14.2 Physics Model of Finite-Size Pencil Beam 226

14.2.1Basic Formulation 227 14.2.2Density-Corrected FSPB 229

14.3Physics Model of Proton Pencil Beam 230 14.4GPU Implementations 231 14.5Experimental Results 233

14.5.1Photon Dose Calculation Results 233 14.5.1.1 Accuracy 234 14.5.1.2 Eciency 238

14.5.2Proton Dose Calculation Results 238 14.6Conclusions and Discussions 239 References 240

real-time adaptation of the treatment to daily anatomical variation [1-16] requires extremely fast and accurate dose calculation engines.