ABSTRACT
CONTENTS 18.1 Introduction 292 18.2 VMAT Optimization Model 293
18.2.1Arc Discretization and Control Points 293 18.2.2Deliverability Constraints 294 18.2.3Basic VMAT Optimization Model 294
18.3GPU-Based Optimization Methods 296 18.3.1Optimization Algorithm 297
18.3.1.1Solving Problem (MP) 298 18.3.1.2 Postprocessing 301
18.3.2GPU Implementation 302 18.3.2.1Single GPU 302 18.3.2.2 Multi-GPU 304
18.3.3Experimental Results 305 18.3.3.1 Multi-GPU 309
18.4 Conclusion 312 References 313
Volumetric-modulated arc therapy (VMAT) is a new modality of cancer treatment. Its initial form was introduced in 1995 as intensity-modulated arc therapy (IMAT) [16]. As an augmentation of intensity modulated radiation therapy (IMRT), IMAT treatments rotate the gantry around the patient in one or multiple arcs while the radiation source stays on. In the meantime, intensity modulation is achieved by using multileaf collimator (MLC) system to dynamically change the eld shape.
