ABSTRACT

Keywords: Asymmetric cyclization, chiral catalysis, one-pot reaction, chiral HPLC, column chromatography

Safety: 3-Buten-2-one (methyl vinyl ketone) is highly volatile and flammable. It will also cause severe skin and eye damage upon contact. Diethyl ether, acetonitrile, hexanes, and ethyl acetate are highly volatile and flammable; work with these solvents in well-ventilated area away from hot objects or sources of ignition. For full MSDS, please visit www.sigmaaldrich.com.