ABSTRACT

The emergence of metagenomics, as a eld to study microbial diversity, was a consequence of the discovery of the fact that the microbial diversity in any environment is much greater than previously realized and accessed by cultivation. This unharvested diversity provides an unlimited source for novel microbial metabolites and some of them may nd a

3.1 Introduction ..........................................................................................................................43 3.2 Metagenomes as source of novel metabolites ..................................................................44 3.3 Prospecting from metagenomes ........................................................................................45