ABSTRACT

Rats and mice have long been regarded as pests in both rural and urban areas, and over the years a number of different rodenticides have been used to control them. These have included zinc phosphide, which degrades to release the toxic gas phosphine, the natural product strychnine, and the cyclodiene endrin, which is a stereoisomer of dieldrin. However, one group of compounds has come to dominate this market-the anticoagulant rodenticides (ARs). The best known of these is warfarin, which is also used in human medicine. The following account is devoted to them.