ABSTRACT

Despite their demonstrated effectiveness, the long term use of microscale neuroprosthetic devices is compromised by the post-implantation tissue reaction that often forms around the device. This book studies ways to improve the tissue reaction to implanted neuroprosthesis by use of a controlled drug release mechanism, quantified by novel measurement techniques. The author describes solutions to the problem of tissue reaction around microscale neuroprostheses and an also examines an improvement in neural stimulation and recording capability. The author, Andre Mercanzini is Review Editor for Frontiers in Neuroengineering. He holds two U.S. patents on microassembly.

chapter 1|34 pages

Introduction

chapter 3|28 pages

Neural Recording and Stimulation

chapter 4|30 pages

in vivo Electrical Impedance Spectroscopy

chapter 5|20 pages

Controlled Release Drug Coatings

chapter 6|6 pages

Conclusion