ABSTRACT

Microelectrodes implanted in nervous tissue can be used to stimulate or

record neural activity, and they hold the promise of allowing neural function

lost to trauma or disease to be regained [1]. A limiting factor with chronically

implanted microelectrodes in the brain is the eventual loss of electrical contact

with neural tissue, due to the post-implantation inflammatory reaction [2-4].

Glial cells rapidly migrate to the implantation site surrounding the device,