ABSTRACT
Microelectrodes implanted in nervous tissue can be used to stimulate or
record neural activity, and they hold the promise of allowing neural function
lost to trauma or disease to be regained [1]. A limiting factor with chronically
implanted microelectrodes in the brain is the eventual loss of electrical contact
with neural tissue, due to the post-implantation inflammatory reaction [2-4].
Glial cells rapidly migrate to the implantation site surrounding the device,