ABSTRACT
An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatment’s efficacy. When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.
TABLE OF CONTENTS
part 1|2 pages
Part I Introductory Material
part 2|2 pages
Contemporary Surrogate Endpoint Evaluation Methods: Multiple-Trial Methods
part 3|2 pages
Part III Software Tools
part 4|2 pages
Part IV Additional Considerations and Further Topics