ABSTRACT

This chapter will tell us the about the real-life implantation possibility of the MIPS-HAp coating as a new genre of bioactive material. Here, we will discuss the MIPS-HAp-coated Ti and SS3161 implants in the rabbit model, goat model, and the dog model. We will also emphasize the biochemical, histological, radiographic, and fluorochrome labeling studies on MIPS-HApcoated intramedullary metallic, i.e., SS3161, pins for fracture repair of surgically created artificial defects in the tibia of New Zealand white rabbits, in particular. The idea behind presentation of these exciting new results is to create further motivation for future researchers to advance the MIPS-HAp coating technology toward the human trial in days to come following, of course, all the mandatory ethical as well as technological issues that may need to be overcome within a reasonable time frame and with resources as deemed appropriate.