ABSTRACT

As an essential micronutrient, selenium is required for a multitude of biological functions. For example, insufficient selenium can lead to male infertility, and several studies have reported on the chemopreventive properties of selenium (Bellinger et al., 2009). Such widespread impact mainly manifests through the action of a limited number of selenoproteins. The requirement for Sec-containing proteins varies across

3.1 Introduction .................................................................................................... 31 3.2 Sec Insertion Process ...................................................................................... 33

3.2.1 Mechanism: A Recoding Event .......................................................... 33 3.2.2 The Essential Factors ..........................................................................34