ABSTRACT
Stereotactic synchrotron radiotherapy (SSRT) and microbeam radiation therapy (MRT) are novel approaches in radiation therapy to treat brain tumors and potentially other tumors using synchrotron radiation. Phase I SSRT clinical trials started in 2014 combining conventional radiotherapy (RT) with one fraction of the treatment delivered at the European Synchrotron Radiation Facility. Although the relative dosimetry is reliable, moving from the current results to absolute dosimetry will be challenging. Radiochromic film energy response curves have to be assessed experimentally. In the single channel measurements, the generated current in one single strip and the isolated guard-ring structure can be measured by two separate electrometers. Recent peak-to-valley dose ratios measurements with a microDiamond detector for MRT application at the Australian Synchrotron were in good agreement with Gafchromic film measurements. Other potential high-resolution types of dosimeters are thermoluminescent dosimeters. Fluorescent nuclear track detectors are a new type of luminescent detectors for dosimetric applications in radiation therapy.
