ABSTRACT

Biophysical Chemistry explores the concepts of physical chemistry and molecular structure that underlie biochemical processes. Ideally suited for undergradate students and scientists with backgrounds in physics, chemistry or biology, it is also equally accessible to students and scientists in related fields as the book concisely describes the fundamental aspects of biophysical chemistry, and puts them into a biochemical context.

The book is organized in four parts, covering thermodynamics, kinetics, molecular structure and stability, and biophysical methods. Cross-references within and between these parts emphasize common themes and highlight recurrent principles. End of chapter problems illustrate the main points explored and their relevance for biochemistry, enabling students to apply their knowledge and to transfer it to laboratory projects.

Features:

  • Connects principles of physical chemistry to biochemistry
  • Emphasizes the role of organic reactions as tools for modification and manipulation of biomolecules
  • Includes a comprehensive section on the theory of modern biophysical methods and their applications

part 1|116 pages

Thermodynamics

chapter 1|2 pages

Systems and Their Surroundings

chapter 3|17 pages

Energetics and Chemical Equilibria

chapter 4|15 pages

Thermodynamics of Transport Processes

chapter 5|16 pages

Electrochemistry

part 2|101 pages

Kinetics

chapter 6|5 pages

Reaction Velocities and Rate Laws

chapter 8|10 pages

Reaction Types

chapter 9|5 pages

Rate-Limiting Steps

chapter 11|29 pages

Steady-State (Enzyme) Kinetics

chapter 12|11 pages

Complex Reaction Schemes and Their Analysis

chapter 13|6 pages

Temperature Dependence of Rate Constants

chapter 14|9 pages

Principles of Catalysis

part 3|143 pages

Molecular Structure and Stability

chapter 15|18 pages

Molecular Structure and Interactions

chapter 16|64 pages

Proteins

chapter 17|38 pages

Nucleic Acids

chapter 18|21 pages

Computational Biology

part 4|365 pages

Methods

chapter 19|96 pages

Optical Spectroscopy

chapter 20|45 pages

Magnetic Resonance

chapter 21|24 pages

Solution Scattering

chapter 22|40 pages

X-ray Crystallography

chapter 23|52 pages

Imaging and Microscopy

chapter 24|23 pages

Force Measurements

chapter 25|10 pages

Transient Kinetic Methods

chapter 26|51 pages

Molecular Mass, Size, and Shape

chapter 27|19 pages

Calorimetry

part 5|26 pages

Appendix

chapter 28|3 pages

Prefixes, Units, Constants

chapter 29|20 pages

Mathematical Concepts Used in This Book