ABSTRACT
Diamonds have been admired throughout time for their beauty, endurance, and rarity as jewels. Interestingly, they are now playing a new role as diagnostic and therapeutic tools in biology and medicine, particularly for nanometer-sized diamonds (Ho ). Diamond nanoparticles, or nanodiamonds (NDs) in short, were rst synthesized by detonation in the former Soviet Union in the s (Danilenko ). Although the discovery was not made public for more than two decades because of the Cold War (Osawa ), these particles brought about by explosive destruction have found wide applications in modern science and technology (Mochalin et al. ).