ABSTRACT

Diamonds have been admired throughout time for their beauty, endurance, and rarity as jewels. Interestingly, they are now playing a new role as diagnostic and therapeutic tools in biology and medicine, particularly for nanometer-sized diamonds (Ho ). Diamond nanoparticles, or nanodiamonds (NDs) in short, were rst synthesized by detonation in the former Soviet Union in the s (Danilenko ). Although the discovery was not made public for more than two decades because of the Cold War (Osawa ), these particles brought about by explosive destruction have found wide applications in modern science and technology (Mochalin et al. ).