ABSTRACT
The emergence of nanotechnology brought new ideas toward solutions of existing problems in biomedical area. One of the biggest challenges was development of scaffolds that can provide a better extracellular matrix (ECM) for cells in tissue engineering. Although cells in our tissues generally vary in size between 5 and 20 µm, it is known that they reside in their niche and their interactions with this microenvironment are at submicron level. Besides, the perfect intracellular and extracellular organizations at micron level are created by building blocks having nanometer sizes. So, the nanoscience and nanotechnology have received more attention toward nding these molecules and their special roles on cell attachment.
