ABSTRACT
The mean duration of the hyperthermic intraperitoneal chemotherapy (HIPEC) procedure was 7.5 hours, and total length of hospital stay was 10 days. Peritoneal carcinomatosis has also been found to be the most common site of disease progression for small bowel adenocarcinoma (SBA). Due to the poor results of traditional treatment, aggressive therapies, including cytoreductive surgery, and HIPEC , have become more attractive options that have been gaining momentum. Extrapolating from experience with HIPEC data of appendiceal and colorectal origins, there have been efforts to employ this modality for SBA. Complete lysis of adhesions was also routinely performed if necessary to improve chemotherapy flow at the time of HIPEC. Similar to HIPEC procedures for other primary sites, the HIPEC is best utilized with systemic therapy, not in lieu of it. HIPEC appears to have lengthened their survival, and likely the quality of life, by an average of more than 18 months.
