Studies of Complex Biological Systems with Applications to Molecular Medicine: The Need to Integrate Transcriptomic and Proteomic Approaches

ELENA SILVESTRI, ASSUNTA LOMBARDI, PIETER DE LANGE, DANIELA GLINNI, ROSALBA SENESE, FEDERICA CIOFFI, ANTONIA LANNI, FERNANDO GOGLIA, AND MARIA MORENO

2.1 INTRODUCTION

Genomic and proteomic data analyses have proven to be essential for an understanding of the underlying factors involved in human disease and for the discovery of diagnostic biomarkers, as well as for the provision of further insights into the metabolic effects mediated by signaling molecules.