ABSTRACT

Nuclear magnetic resonance (NMR) is a complex physical phenomenon, but it can be expressed simply as follows: Magnetically active nuclei placed into an external magnetic field are excited by radiofrequency irradiation, and the energy absorbed due to the irradiation (resonance) is registered as a NMR signal. Nuclei having different environments will correspond to different energies and hence different signals, and the resulting totality of the signals forms a one-dimensional NMR spectrum. Generally, the NMR spectra are recorded as plots of line intensity vs. resonance frequency, where the number of spectral lines corresponds to the number of non-equivalent nuclei dictated by molecular structure and molecular symmetry and depends on spectral resolution.