ABSTRACT
The diffi culty in the functional understanding of the genome lies not only in the high number of functional elements but also in the fact that they interact in entangled pathways, giving rise to global properties whose relationships with the specifi c role and function of each element are diffi cult to discern. So, increasingly, the study of the genome is approached with a perspective that, along with the properties and functions of single genes, aspects of their interactions are also taken into account. A straightforward way to study an interacting system is to represent it through a network. Hence network biology has received much interest and interdisciplinary efforts, combining biological problems with tools provided from physics or computer
IBE, Evolutionary Biology Institute (CSIC-Pompeu Fabra University) UPF-PRBB, Doctor Aiguader 88, 08003 Barcelona, Catalonia, Spain.
