ABSTRACT

An accessible and enjoyable introduction to pathology and the mechanisms of disease, this book puts pathology into its historical, scientific and clinical context. Organized in four main themes - What is a Disease, Defense Against Disease, Circulatory Disorders and Disorders of Cell Growth - the text highlights key mechanisms and their interplay in producing symptoms, signs and disease. Supplemented throughout with colorful cartoons, and much-praised clinical scenarios, this entertaining look at pathology offers historical anecdotes and helpful key-points boxes.

part |2 pages

PART 1 Disease, health and medicine

chapter 1|33 pages

What causes disease?

chapter 2|47 pages

What are the common mechanisms of disease?

part |2 pages

PART 2 Defence against disease

part |2 pages

Part 3 Features of cardiovascular disorders

chapter 7|20 pages

Vascular occlusion and thrombosis

chapter 8|23 pages

Atherosclerosis and hypertension

chapter 9|33 pages

Circulatory failure

part |2 pages

Part 4 Cell growth and its disorders

chapter |2 pages

Introduction: A brief history of cancer

chapter 10|10 pages

Benign growth disorders

chapter 11|15 pages

Malignant neoplasms

chapter 12|12 pages

What causes cancer?

chapter 13|22 pages

Molecular genetics of cancer

chapter 14|7 pages

The behaviour of tumours

chapter 15|12 pages

The clinical effects of tumours

chapter |1 pages

Epilogue

chapter |8 pages

Index

part |1 pages

PART 1: Symptoms

chapter |3 pages

Case 1: Intermittent chest pain

chapter |4 pages

Case 2: Shortness of breath

chapter |3 pages

Case 3: Difficulty in passing urine

chapter |4 pages

Case 4: Difficulty in swallowing

chapter |4 pages

Case 5: Easy bruising

chapter |3 pages

Case 6: Coughing up blood

chapter |4 pages

Case 7: Fever and cough

chapter |4 pages

Case 8: Abdominal pain and weight loss

chapter |4 pages

Case 9: A mixture of problems

chapter |4 pages

Case 10: The ancient mimic

part |1 pages

PART 2: Signs

chapter |4 pages

Case 12: Permanent neurological signs

chapter |3 pages

Case 13: A cervical mass

chapter |4 pages

Case 14: Haematuria clinic

chapter |4 pages

Case 15: Reduced air entry

chapter |4 pages

Case 16: Enlarged lymph nodes

chapter |4 pages

Case 17: More enlarged lymph nodes

chapter |4 pages

Case 18: Tachycardia and tachypnoea

chapter |6 pages

Case 19: A social drinker

chapter |4 pages

Case 20: Indigestion

chapter |4 pages

Case 21: The diabetic clinic

part |1 pages

PART 3: Investigations

chapter |4 pages

Case 22: Abnormal full blood count

chapter |4 pages

Case 23: Complex blood results

chapter |3 pages

Case 24: An abnormal smear test

chapter |3 pages

Case 25: An abnormal mammogram

chapter |3 pages

Case 26: An abnormal baby

chapter |4 pages

Case 27: The genetic clinic

chapter |4 pages

Case 28: Fracture clinic

chapter |4 pages

Case 29: Acute back pain

chapter |3 pages

Case 30: MRI diagnosis

chapter |4 pages

Case 31: Investigation after death

chapter |3 pages

Case 32: Sudden death of a child

chapter |4 pages

Case 33: Jaundice

part |1 pages

PART 4: Treatment

chapter |3 pages

Case 35: Novel chemotherapy

chapter |4 pages

Case 36: Supporting haematopoiesis

chapter |4 pages

Case 37: A prophylactic resection

chapter |4 pages

Case 38: A chronic autoimmune disease

chapter |4 pages

Case 39: Keeping the pump pumping

chapter |4 pages

Case 40: Radiologist or surgeon?

chapter |6 pages

Case 41: Organ transplantation

part |1 pages

PART 5: Complex management

chapter |4 pages

Case 43: A life-threatening rash

chapter |4 pages

Case 44: A first seizure

chapter |5 pages

Case 45: Febrile and unconscious

chapter |3 pages

Case 46: Multi-organ disease

chapter |3 pages

Case 48: Certifying the cause of death

chapter |3 pages

Case 49: Referring cases to the coroner

chapter |3 pages

Case 50: Your worst nightmare!