ABSTRACT

The prime interest in pharmaceutics relative to powder flow is that it affects tableting (and hard-shell) operation in several ways.

The flow rate of powders is affected by several properties:

1. The shape of the particle 2. The size of the particle 3. The roughness (rugosity, fractal dimension) of the particle

4. The chemical nature of the powder (e.g., the cohesion) 5. The moisture content

The first sections in the following will deal with the flow of (a) first one fairly monodisperse component, then (b) a polydisperse component or a mixture of two components. If not otherwise specified in the heading, it is example (a) that is being discussed.