ABSTRACT

Time (min) Figure 4 Binding of three genetically related strains of B. dennatitidis yeast to human macrophages. Attachment index (number of yeasts bound per 100 macrophages) was detennined serially over 60 min during incubation at 37"C. Data are the mean ± SEM of four experiments with wild-type strain 26199. and mean of two experiments each with mutants 60915 and 60916. (From Ref. 50.)

phagocytes. as has been described during 12-hr cocultures of these yeasts with murine macrophages (see below) [51).