ABSTRACT

Biological tissue is relatively transparent to electromagnetic radiation with fre­ quencies in the megahertz or radio-frequency (RF) range. Nuclear magnetic reso­ nance (NMR) techniques utilize this property to obtain various anatomical, biochemical, and physiological information from tissue. Magnetic resonance imaging (MRI) of protons (Ή) is now a widely accepted clinical imaging modal­ ity, primarily due to its ability to image soft tissue like the white matter and grey matter of the brain. But apart from Ή MRI, NMR can interrogate many other nuclei in the tissue. A list of isotopes of the elements that have been studied in biological samples by NMR is given in Table 10.1 in order of decreasing absolute sensitivity.