ABSTRACT

The additio n o f th e las t four mannos e an d al l the glucos e residues , a s wel l a s th e

Figure 18.1 9 Dolicho l structur e (upper ) an d it s functio n i n glycoprotei n biosynthesi s (lower). Dolicho l i s show n i n it s dephosphorylate d state . (Reproduce d b y permissio n from Kelle r RK. Dolicho l metabolism in the rat . Trends Biochem Sci November:443, 1987. )

transfer o f th e carbohydrat e t o a polypeptid e chain , take s plac e o n th e lumina l

side o f th e system .