ABSTRACT
Acetic anhydride is a colorless liquid with a pungent odor similar to acetic acid. Acetic anhydride has been manufactured and used for many years. The first synthesis was reported in 1852 and was accomplished by the reaction of potassium acetate with benzoyl chloride [1]. This method has been replaced by numerous industrial processes for the large-scale production of acetic anhydride. Nearly a million metric tons are produced annually, and it is used primarily for acetylation of the hydroxyl group of various substrates. The purpose of this chapter is to provide chemical and physical information on acetic anhydride. Commercial production of anhydride is also covered, and emphasis is placed on emerging technology related to this important industrial chemical.
