ABSTRACT

I.INTRODUCTION Retinoidscontroltissuegrowthanddifferentiationatallphasesoflifefrom conception,togrowthoftheembryoandmaintenanceoftheadultorganism. Researchindermatology(1),embryogenesis(2),epithelialdifferentiation(3), tumorigenesisandchemoprevention(4),fieldnutritionindevelopingcountries (5),andotherareashasutilizedretinoidsasimportanttoolstounderstandkey processesthatcontroldiversebiologicalevents.