ABSTRACT
The manipulation of biological organisms or their components for complete or partial purifi cation of contaminated ecosystems is an old technology the application of which has increased tremendously due to elucidation made possible by recent advances in molecular genetics, bio chemistry, and the ecology of microorganisms. In order to derive maximum environmental and industrial ecological benefits from current remediation biotechnology, it is important to iden tify and solve specific problems that remain both for basic research and for field practice. This chapter presents realized and potential problems confronting current attempts to implement en vironmental bioremediation schemes, and research approaches to solve these problems. The focus of the chapter is on problems of molecular and organismic dimensions.