ABSTRACT

Awouafack, M.D. et al., J. Nat. Prod., 2011, 74, 272-278 (Lachnoisoflavone A, activity)

[672948-78-6]

C29H34O4 446.585 Constit. of the roots of Artocarpus lakoocha and Artocarpus petelotii. Shows moderate antimycobacterial activity against Mycobacterium tuberculosis H37Ra. Shows cytotoxic activity against breast and nasopharyngeal carcinoma cell lines. Semisolid. lmax 205 (log e 4.49); 250 (log e 3.77); 296 (log e 3.88) (MeOH). Puntumchai, A. et al., J. Nat. Prod., 2004, 67,

485-486 (Lakoochin B, struct, antimycobacterial activity, cytotoxicity)

L-3Lanaroflavone 8-[4-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)phenoxy]-5,7-dihydroxy-2-(4hydroxyphenyl)-4H-1-benzopyran-4-one, 9CI [521-50-6]

O

OH

HO

O

O

O

HO

OH O

C30H18O10 538.466 Isol. from Lanaria lanata and Campnosperma panamense. Shows antimalarial

and leishmanicidal activity. Fine yellow needles (MeOH). Mp 294-2968. This struct. originally claimed for Hinokiflavone, H-189 in 1966.