ABSTRACT
The Ca2+-ATPase of sarcoplasmic reticulum is absolutely dependent upon phospholipids for activity (Kielley and Meyerhof, 1948a, b, 1950; Ebashi, 1958; Martonosi, 1963, 1964, 1971, 1972a, b). This generated considerable interest in the lipid composition of sarcoplasmic reticulum (Waku, 1977) and in the possible modes of involvement of phospholipids (Bennett et al., 1980; Martonosi and Beeler, 1983; Hidalgo, 1985b, 1987; A.G.Lee et al., 1986; A.G.Lee, 1987, 1988, 1991; Lentz, 1988a; A.G.Lee and East, 1993) and cholesterol (Yeagle, 1989) in ATP hydrolysis and Ca2+ transport.
