ABSTRACT

A key item in the selection and design of an affinity chromatographic method is the choice of support material. The supports used in affinity chromatography must meet several requirements. Ideally, such a support should be inexpensive and allow solutes to have rapid, unhindered access to the immobilized affinity ligand. In addition, the support should play a completely passive role during the separation while also being able to couple the desired affinity ligand.