ABSTRACT

It is worth noting that another technique has recently been reported for visually discerning all human chromosomes in distinct colors (55) . In contrast to SKY, this technique utilizes conventional filter technology and requires sequential exposures of the hybridized chromosomes with six op­ tical filters to obtain a "color karyotype. ' ' Whereas SKY allows for a one­ step image acquisition, this technique requires multiple images to be ac­ quired for visualization of all chromosomes.