ABSTRACT
Cytogenetic analysis of neoplastic disease has become a significant part of diagnostic pathology. Chromosomal evaluation of hematologic specimens (i .e . , blood, bone marrow, lymph nodes) and solid neoplasms plays a crucial role in diagnostic surgical pathology. Such studies have been shown to be particularly valuable in the diagnosis and prognosis of hematologic disorders ( 1 -5) . Chromosomal evaluations have also improved the diagnostic accu racy of solid neoplasms, especially bone and soft tissue tumors (6-8) .
