ABSTRACT
Erythrocyteautoantibodiesmaybebenign,presentintheplasmaofhealthyindividuals,or pathogenic,causingautoimmunehemolysis(1,2).Autoimmunehemolyticanemia(AIHA) consistsoftwomajorclinicaldisorders:coldhemagglutinindisease(coldAIHA)duetoanlgM antibodythatpreferentiallyagglutinatesredbloodcells(RBCs)inthecold(4--24°C)andthe morecommonsyndromeofwarmreactive(37°C)immunoglobulinG(lgG)-inducedautoimmunehemolyticanemia(warmAIHA).
