ABSTRACT
EPA TSCA 8(E) NOTICE 8EHQ-0383-0474 THE CELANESE CORP. PROVIDED PRELIMINARY FINDINGS FROM CHRONIC INHALATION STUDY IN WHICH RATS EXPOSED TO ACETALDEHYDE VAPOR OF 0, 750, 1500, OR 3000 PPM REVEALED HYPER-AND METAPLASTIC EPITHELIUM WITH MASSIVE KERATINIZATION IN NOSE, AND AT 3000 PPM IN LARYNX. CARCINOMA FROM RESPIRATORY EPITHELIUM FOUND IN TOP-DOSE RATS; NASAL CARCINOMA. ACETALDEHYDE CAPABLE OF INDUCING NASAL CARCINOMAS IN RATS.
