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screen. Chemicals which are shown to be mutagenic in Phase I assays progress to Phase II. In addition, a certain number of chemicals giving negative results in Phase I are committed also to further testing in Phase II, based primarily on known biological activity of structurally related compounds, and on estimated levels of human exposure. Chemicals which are positive mutagens in Phase progress to Phase III. III. WORLD HEALTH ORGANIZATION'S (WHO) INTERNATIONAL AGENCY FOR RESEARCH ON CANCER (IARC) IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans In the World Health Organization's International Agency for Research on Cancer (IARC) initiated a program of evaluation of the carcinogenic risk of chemicals to humans. "The objective of the program to elaborate and publish in the form of monographs, critical reviews of data on carcinogenicity for groups of chemicals to which humans are known to be exposed, to evaluate these data in terms of human risk . . . and to indicate where additional research efforts are needed." The IARC Monographs are recognized an authoritative source of information on the carcinogenicity of environmental chemicals. The first users' survey, made in 1976, indicates that the monographs are consulted routinely by various agencies in 24 countries. IV. OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION (OSHA) A List of Substances Which May Be Candidates for Further Scientific Review and Possible Identification, Classification and Regulation Potential Occupational Carcinogens. Publication of this list by the Occupational Safety and Health Administration the first action taken in following the "Cancer Standard" procedures promulgated by OSHA in January, 1980.
DOI link for screen. Chemicals which are shown to be mutagenic in Phase I assays progress to Phase II. In addition, a certain number of chemicals giving negative results in Phase I are committed also to further testing in Phase II, based primarily on known biological activity of structurally related compounds, and on estimated levels of human exposure. Chemicals which are positive mutagens in Phase progress to Phase III. III. WORLD HEALTH ORGANIZATION'S (WHO) INTERNATIONAL AGENCY FOR RESEARCH ON CANCER (IARC) IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans In the World Health Organization's International Agency for Research on Cancer (IARC) initiated a program of evaluation of the carcinogenic risk of chemicals to humans. "The objective of the program to elaborate and publish in the form of monographs, critical reviews of data on carcinogenicity for groups of chemicals to which humans are known to be exposed, to evaluate these data in terms of human risk . . . and to indicate where additional research efforts are needed." The IARC Monographs are recognized an authoritative source of information on the carcinogenicity of environmental chemicals. The first users' survey, made in 1976, indicates that the monographs are consulted routinely by various agencies in 24 countries. IV. OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION (OSHA) A List of Substances Which May Be Candidates for Further Scientific Review and Possible Identification, Classification and Regulation Potential Occupational Carcinogens. Publication of this list by the Occupational Safety and Health Administration the first action taken in following the "Cancer Standard" procedures promulgated by OSHA in January, 1980.
screen. Chemicals which are shown to be mutagenic in Phase I assays progress to Phase II. In addition, a certain number of chemicals giving negative results in Phase I are committed also to further testing in Phase II, based primarily on known biological activity of structurally related compounds, and on estimated levels of human exposure. Chemicals which are positive mutagens in Phase progress to Phase III. III. WORLD HEALTH ORGANIZATION'S (WHO) INTERNATIONAL AGENCY FOR RESEARCH ON CANCER (IARC) IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans In the World Health Organization's International Agency for Research on Cancer (IARC) initiated a program of evaluation of the carcinogenic risk of chemicals to humans. "The objective of the program to elaborate and publish in the form of monographs, critical reviews of data on carcinogenicity for groups of chemicals to which humans are known to be exposed, to evaluate these data in terms of human risk . . . and to indicate where additional research efforts are needed." The IARC Monographs are recognized an authoritative source of information on the carcinogenicity of environmental chemicals. The first users' survey, made in 1976, indicates that the monographs are consulted routinely by various agencies in 24 countries. IV. OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION (OSHA) A List of Substances Which May Be Candidates for Further Scientific Review and Possible Identification, Classification and Regulation Potential Occupational Carcinogens. Publication of this list by the Occupational Safety and Health Administration the first action taken in following the "Cancer Standard" procedures promulgated by OSHA in January, 1980.
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