ABSTRACT
IARC VOL 41 1986 LIMITED EVIDENCE THAT OCCUPATIONAL EXPOSURES TO CHLOROPHENOXY HERBICIDES ARE CARCINOGENIC TO HUMANS. EVALUATION OF EVIDENCE FOR CARCINOGENICITY IN ANIMALS AND SHORT-TERM TEST ACTIVITY ARE DISCUSSED IN IARC 1982 SUPPLEMENT 4, PP 101-103, 211-212 AND 235-238 AND IN IARC 1983 VOL 30, PP 255-269. HERBICIDES
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NCI CARC TRS 85 DHEW PUB NO 78-1335 UNDER THE CONDITIONS OF THIS BIOASSAY, DIETARY ADMINISTRATION OF 4-CHLORO-M-PHENYLENEDIAMINE WAS CARCINOGENIC TO THE EXPERIMENTAL ANIMALS, CAUSING AN INCREASED INCIDENCE OF HEPATOCELLULAR TUMORS IN MALE B6C3Fl MICE AND AN INCREASED INCIDENCE OF ADRENAL PHEOCHROMOCYTOMAS IN MALE FISCHER 344 RATS.
