ABSTRACT
AND WITHOUT REDUCTION BY DITHIONITE, BUT ONLY AFTER S-9 ACTIVATION.
REPORT 01
REPT'D USE
CAS NO
CPSC ANTHRAQUINONE DYES MONOGRAPH OCT 81 C.I. MORDANT RED 11 BINDS TO DNA IN THE B. SUBTILIS REC ASSAY AND PRODUCES CHROMOSOMAL FRAGMENTATION IN ONION PLANTS. THE DYE PRODUCED MUTATIONS IN SALMONELLA WITH OR WITHOUT ACTIVATION. PAINTS/VARNISHES AND AEROSOLS
81-54-9 CHEM NAME: *** C.I. NATURAL RED 8 (PURPURIN) REPORT 01
REPT'D USE
CPSC ANTHRAQUINONE DYES MONOGRAPH OCT 81 PURPURIN WAS MUTAGENIC IN SALMONELLA AND WAS TOXIC AT HIGHER CONCENTRATIONS. MUTAGENICITY OF THIS CHEMICAL DECREASED AFTER TREATMENT WITH LIVER MICROSOMAL FRACTION. PURPURIN BINDS TO, BUT DOES NOT DAMAGE, THE DNA OF B. SUBTILIS AND E. COLI. NO AVAILABLE PRODUCTION OR USE DATA. NO LISTING ON TSCA INVENTORY
REPORT 01
REPT'D USE
CAS NO
IARC MONOGRAPH 23 1980 EXPERIMENTS IN RATS EXPOSED TO CHROMIC (III) OXIDE BY ORAL ADMINISTRATION, BRONCHIALIMPLANTATION, IP, INTRATRACHEAL, AND INTRAPLEURRAL INJECTION WERE INADEQUATE TO EVALUATE CARCINOGENICITY. PIGMENT, ABRASIVES, REFRACTORY MATERIAL, PAINT/VARNISH, AND AEROSOL
REPORT 01 CPSC MONOGRAPH ON MONOAZO DYES AUG 81 C.I. PIGMENT ORANGE 5 WAS NEGATIVE IN DERMAL AND ORAL CARCINOGENICITY STUDIES IN DOGS AND MICE. FEEDING STUDIES EXAMINING REPRODUCTIVE AND TERATOGENIC EFFECTS WERE NEGATIVE IN RATS AND RABBITS. THERE WERE POSITIVE RESULTS IN THREE SEPARATE AMES TESTS FOR MUTAGENICITY.
