ABSTRACT

Aluminum Toxicokinetics Aluminum is an ubiquitous but nonessential metal. For the general popula­ tion, food constitutes the main source of exposure to aluminum. The alumi­ num content of most foodstuffs is less than 1 m g /100 g (Ott, 1985). The daily food intake usually ranges from less than 10 mg to 160 mg (Elinder and Sjogren, 1986; Lauwerys, 1999). The use of aluminum-coated vessels (partic­ ularly when acidic foodstuffs are stored in aluminum utensils), treatment of water with aluminum compounds as flocculants in the purification process, aluminum-containing drugs (antacids, phosphate binders), aluminum-con­ taminated parenteral fluids (parenteral nutrition, intravenous solutions, con­ taminated dialysates), and aluminum-based food additives are the other potential main sources of nonoccupational hum an exposure. It is generally accepted that in healthy persons, aluminum is poorly (less than 1%) absorbed by the oral route (Ihle and Becker, 1985; Kaehny et al., 1977; Ott, 1985; Priest et al., 1998).