ABSTRACT
Considerable analytical progress in food-stuffs contamination assessment and analysis has been made over the past decade, when hyphenated techniques involving highly efcient separation and sensitive detection have become the techniques of choice. Among them, mass spectrometry (MS) has gained tremendous popularity due to its unparalleled sensitivity and specicity, high resolution, and a wide dynamic range. The combination with advanced, high-throughput separation techniques, such as gas chromatography-MS (GC-MS), liquid chromatography-MS (LC-MS), and more recently, capillary electrophoresis-MS (CE-MS), have widened the applications of MS technology, offering enormous opportunities for detection and conrmation. Hence, methods based on separation with MS detection are acknowledged as the major useful and authoritative methods for the determination of harmful or dangerous compounds in food.
