ABSTRACT
The interpretation of signals obtained from ion-selective electrodes depends upon reliable calibration of the electrode system. It must always be remembered that it is a potential difference (p.d.) between the ion-selective and reference electrode that is measured and the interpretation of this p.d. in terms of ionic concentrations is achieved by a calibration curve. Thus note must be taken of the range over which the electrode will be reasonably responsive to the primary ion, the extent to which other ions will interfere with the signal and the stability of other potentials in the overall system (see chapter 2).
