ABSTRACT
The first report on the analytical use of an aqueous solution of a surfactant, above its critical micellar concentration (CMC), as mobile phase in reversed-phase liquid chromatography (RPLC) was published in 1980.[1] The technique, named micellar liquid chromatography (MLC), is an interesting example of the modification of the chromatographic behavior taking advantage of secondary equilibria to vary both retention and selectivity.
