ABSTRACT

An imminent risk of clinical events such as coronary heart disease (CHD) death is extremely low among youth. This notion, however, is gradually being modified because of the potential impact of obesity on early derangements in the metabolic framework of children and adolescents. Longitudinal

Introduction .................................................................................................................................... 281 Tracking of Obesity from Childhood to Adulthood ....................................................................... 281 Biomarkers/Risk Factors and Surrogate End Points in CVD ........................................................ 283 Surrogate Measures of Target Organ Damage ...............................................................................284