ABSTRACT

Volumes in the Proven Synthetic Methods Series address the concerns many chemists have regarding irreproducibility of synthetic protocols, lack of identification and characterization data for new compounds, and inflated yields reported in chemical communications—trends that have recently become a serious problem.

Featuring contributions from world-renowned experts and overseen by a highly respected series editor, Carbohydrate Chemistry: Proven Synthetic Methods, Volume 4 compiles reliable synthetic methods and protocols for the preparation of intermediates for carbohydrate synthesis or other uses in the glycosciences.

Exploring carbohydrate chemistry from both the academic and industrial points of view, this unique resource brings together useful information into one convenient reference. The series is unique among other synthetic literature in the carbohydrate field in that, to ensure reproducibility, an independent checker has verified the experimental parts involved by repeating the protocols or using the methods.

The book includes new or more detailed versions of previously published protocols as well as those published in not readily available journals. The essential characteristics of the protocols presented are reliability, updated characterization data for newly synthesized substances and the expectation of wide utility in the carbohydrate field. The protocols presented will be of wide use to a broad range of readers in the carbohydrate field and the life sciences, including undergraduates taking carbohydrate workshops.

section I|90 pages

Synthetic Methods

chapter 1|8 pages

Picoloyl-Protecting Group in Oligosaccharide Synthesis

Installation, H-Bond-Mediated Aglycone Delivery (HAD), and Selective Removal

section II|262 pages

Synthetic Intermediates

chapter 11|6 pages

Synthesis of 4-Nitrophenyl β-d-galactofuranoside

A Useful Substrate for β-d-Galactofuranosidases Studies

chapter 16|8 pages

1,2,3,5,6-Penta-O-tert-butyl(dimethyl)silyl-β-d-galactofuranose

A Versatile Glycosylating Agent for Galactofuranosylation

chapter 30|8 pages

Fluorine-Containing Carbohydrates

Synthesis of 6-Deoxy-6-fluoro-1,2:3,4-di-O-isopropylidene-α-d-galactopyranose