ABSTRACT

An invaluable resource for computational biologists and researchers from other fields seeking an introduction to the topic, Chromatin: Structure, Dynamics, Regulation offers comprehensive coverage of this dynamic interdisciplinary field, from the basics to the latest research. Computational methods from statistical physics and bioinformatics are detailed whenever possible without lengthy recourse to specialized techniques.

chapter 1|20 pages

DNA and the nucleosome

chapter 2|34 pages

DNA elasticity and topology

chapter 3|18 pages

Gene regulation without and with chromatin

chapter 4|46 pages

Histones and histone-acting enzymes

chapter 5|20 pages

Regulating chromatin

chapter 7|4 pages

Conclusions and Outlook